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Istovremena primena leka Bensedin i opioida (lekova za ublažavanje jakih bolova, lekova za supstitucionu terapiji i određenih lekova protiv kašlja) povećava rizik od pospanosti, otežanog disanja (respiratorna depresija), kome što sve može biti životno ugrožavajuće. Zbog toga istovremenu primenu treba razmotriti samo ukoliko druge terapijs
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The clinical trial practical experience with eszopiclone revealed no proof of a significant withdrawal syndrome. Nonetheless, the following adverse activities included in DSM-IV requirements for uncomplicated sedative/hypnotic withdrawal ended up reported throughout medical trials subsequent placebo substitution transpiring in forty eight hours pur